António de Almeida

Professor Catedrático
António Almeida

amalmeida@ucp.pt

Generic Bio

Participação na FM-UCP

  • Diretor da Faculdade 
  • Mentor 

 

Áreas de Atividade

Hematologia Clínica | Anemia | Neoplasias Mieloides Crónicas | Epigenética | Educação Médica

 

Atividade Profissional

  • Faculdade de Medicina da Universidade Católica (FM-UCP) 
  • Centro de Investigação Interdisciplinar em Saúde (CIIS) – Plataforma CatólicaMed
  • Hospital da Luz Lisboa   

 

Formação

  • Universitdade: University of Cambridge 
  • Junho 1990: BA Hons (Cantab) 
  • Medical School: Addenbrooke's Hospital, Cambridge 
  • Dezembro 1993: MB Bchir (Cantab) 

 

Qualificações Pós-Graduação

  • Fevereiro 1997: MRCP (Lond) 
  • Setembro 2001: MRCPath 
  • Junho 2002: Certificado de conclusão de formação especializada (CCST) em Hematologia 
  • Maio 2007: PhD Imperial College 
  • Maio 2015: Consultor em Hematologia na Ordem dos Médicos 
  • Maio 2021: Agregação à Universidade Católica Portuguesa  

 

Resumo da Carreira Profissional

  • Janeiro 1993 – Set 1997: Interno geral, Cambridge e St George’s Hospital Londres
  • Setembro 1997 – Jun 2003: Interno especialidade hematologia Hospitais zona Norte de Londres (Hammersmith, Royal Free, Great Ormond Street, St Mary’s, Central Middlesex) 
  • Junho 2003 - Jun 2006: Leukaemia Research Fund Clinical Research Fellow 
  • Setembro 2006 – set 2017: Hematologista IPO Lisboa 
  • Setembro 2017 - Presente: Diretor de serviço de Hematologia, Hospital da Luz Lisboa 
  • Março 2021 - Presente: Diretor da Faculdade de Medicina da UCP 

 

Línguas

Português | Inglês | Italiano | Espanhol | Francês

 

Outros Interesses

  • O mais feliz no mar: barco ou surf 
  • Uso golf para estragar um bom passeio 
  • Fascínio por pássaros 
  • Boa comida e bebida 

 

Programas:
Modules / Courses:
  • Domínio de Competências Profissionais
Artigo

European Stop Tyrosine Kinase Inhibitor Trial (EURO-SKI) in Chronic Myeloid Leukemia: Final Analysis and Novel Prognostic Factors for Treatment-Free Remission

António de Almeida (with Francois-Xavier Mahon). 2024. Journal of Clinical Oncology
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Artigo

Automated identification of leukocyte subsets improves standardization of database-guided expert-supervised diagnostic orientation in acute leukemia: a EuroFlow study

António de Almeida (with Ludovic Lhermitte). 2021. Modern Pathology
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Artigo

Outcomes of patients with chronic myelomonocytic leukaemia treated with non-curative therapies: a retrospective cohort study

António de Almeida (with Lisa Pleyer). 2021. The Lancet Haematology
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Artigo

Phase III, Randomized, Placebo-Controlled Trial of CC-486 (Oral Azacitidine) in Patients With Lower-Risk Myelodysplastic Syndromes

António de Almeida (with Guillermo Garcia-Manero). 2021. Journal of Clinical Oncology
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Artigo

Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia—From Molecular Mechanisms to Clinical Relevance

António de Almeida (with Raquel Alves). 2021. Cancers
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Artigo

Spontaneous Tumor Lysis Syndrome: A Rare Presentation in Plasmablastic Lymphoma

António de Almeida (with Joana Infante). 2021. Journal of Hematology
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Artigo

The Activation of Endothelial Cells Relies on a Ferroptosis-Like Mechanism: Novel Perspectives in Management of Angiogenesis and Cancer Therapy

António de Almeida (with Filipa Lopes-Coelho). 2021. Frontiers in Oncology
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Artigo

Achievement of red blood cell transfusion independence in red blood cell transfusion-dependent patients with lower-risk non-del(5q) myelodysplastic syndromes correlates with serum erythropoietin levels.

António de Almeida 2020. Leukemia & lymphoma
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Artigo

Guideline-based indicators for adult patients with myelodysplastic syndromes.

António de Almeida 2020. Blood advances
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Artigo

Impact of somatic mutations on response to lenalidomide in lower-risk non-del(5q) myelodysplastic syndromes patients.

António de Almeida 2020. Leukemia
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Artigo

Monocytes as Endothelial Progenitor Cells (EPCs), Another Brick in the Wall to Disentangle Tumor Angiogenesis.

António de Almeida 2020. Cells
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Artigo

Novel dynamic outcome indicators and clinical endpoints in myelodysplastic syndrome; the European LeukemiaNet MDS Registry and MDS-RIGHT project perspective

António de Almeida (with Theo De Witte). 2020. Haematologica
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Artigo

Oral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia in First Remission.

António de Almeida 2020. The New England journal of medicine
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Artigo

Clinical Benefit-Risk Profile of Lenalidomide in Patients With Lower-risk Myelodysplastic Syndromes Without del(5q): Results of a Phase III Trial

António de Almeida (with Guillermo Garcia-Manero). 2019. Clinical Lymphoma Myeloma and Leukemia
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Artigo

Everolimus in combination with Imatinib overcomes resistance in Chronic myeloid leukaemia.

António de Almeida 2019. Medical oncology (Northwood, London, England)
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Artigo

Impact of treatment with iron chelation therapy in patients with lower-risk myelodysplastic syndromes participating in the European MDS registry.

António de Almeida 2019. Haematologica
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Artigo

Less iron improves MDS haematopoiesis.

António de Almeida 2019. British journal of haematology
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Artigo

Negative MR<sup>4·0</sup> chronic myeloid leukaemia and its possible implications for treatment-free remission.

António de Almeida 2019. British journal of haematology
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Artigo

New prospects for the management of cardiovascular effects of tyrosine kinase inhibitors in patients with chronic myeloid leukemia.

António de Almeida 2019. Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
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Artigo

Safety and efficacy findings from the open-label, multicenter, phase 3b, expanded treatment protocol study of ruxolitinib for treatment of patients with polycythemia vera who are resistant/intolerant to hydroxyurea and for whom no alternative treatme...

António de Almeida 2019. Leukemia & lymphoma
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Artigo

Vorinostat synergizes with antioxidant therapy to target myeloproliferative neoplasms

António de Almeida & Bruno António Caetano Cardoso (with Cardoso, B.A.). 2019. Experimental Hematology
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Artigo

Considerations for Treatment-free Remission in Patients With Chronic Myeloid Leukemia: A Joint Patient–Physician Perspective

António de Almeida (with Giuseppe Saglio). 2018. Clinical Lymphoma Myeloma and Leukemia
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Artigo

Early platelet count kinetics has prognostic value in lower-risk myelodysplastic syndromes.

António de Almeida 2018. Blood advances
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Artigo

Evaluation of induction chemotherapies after hypomethylating agent failure in myelodysplastic syndromes and acute myeloid leukemia.

António de Almeida 2018. Blood advances
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Artigo

Evidence-Based Criteria for Tyrosine Kinase Inhibitor Interruption in Pregnancy.

António de Almeida 2018. Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Artigo

Hematology traning in Europe

António de Almeida (with A. Almeida). 2018. International Journal of Laboratory Hematology
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Artigo

Should more MDS patients be treated with immune-suppression?

António de Almeida (with Antonio Almeida). 2018. Leukemia Research
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Artigo

Clinical benefit of eculizumab in patients with no transfusion history in the International Paroxysmal Nocturnal Haemoglobinuria Registry

António de Almeida (with Almeida, A.M.). 2017. Internal Medicine Journal
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Artigo

Clinical outcomes of 217 patients with acute erythroleukemia according to treatment type and line: A retrospective multinational study

António de Almeida (with Almeida, A.M.). 2017. International Journal of Molecular Sciences
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Artigo

Clinical outcomes of AML patients treated with Azacitidine in Portugal: A retrospective multicenter study

António de Almeida (with Almeida, A.). 2017. Leukemia Research Reports
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Artigo

Different clinical characteristics of paroxysmal nocturnal hemoglobinuria in pediatric and adult patients

António de Almeida (with Urbano-Ispizua, Á.). 2017. Haematologica
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Artigo

HDAC8 overexpression in mesenchymal stromal cells from JAK2<sup>+</sup>myeloproliferative neoplasms: A new therapeutic target?

António de Almeida (with Ramos, T.L.). 2017. Oncotarget
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Artigo

Real life experience with frontline azacitidine in a large series of older adults with acute myeloid leukemia stratified by MRC/LRF score: results from the expanded international E-ALMA series (E-ALMA+)

António de Almeida (with Falantes, J.). 2017. Leukemia and Lymphoma
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Artigo

Recent advances in the treatment of lower-risk non-del(5q) myelodysplastic syndromes (MDS)

António de Almeida (with Almeida, A.). 2017. Leukemia Research
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Artigo

Acute myeloid leukemia in the older adults

António de Almeida (with Almeida, A.M.). 2016. Leukemia Research Reports
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Artigo

Design and rationale of the QUAZAR lower-risk MDS (AZA-MDS-003) trial: a randomized phase 3 study of CC-486 (oral azacitidine) plus best supportive care vs placebo plus best supportive care in patients with IPSS lower-risk myelodysplastic syndromes a...

António de Almeida (with Garcia-Manero, G.). 2016. BMC Hematology
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Artigo

Design of the randomized, Phase III, QUAZAR AML Maintenance trial of CC-486 (oral azacitidine) maintenance therapy in acute myeloid leukemia

António de Almeida (with Roboz, G.J.). 2016. Future Oncology
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Artigo

Randomized phase III study of lenalidomide versus placebo in RBC transfusion-dependent patients with lower-risk non-del(5q) myelodysplastic syndromes and ineligible for or refractory to erythropoiesis-stimulating agents

António de Almeida (with Santini, V.). 2016. Journal of Clinical Oncology
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Artigo

Epigenetic Alterations in Fanconi anaemia: Role in pathophysiology and therapeutic potential

António de Almeida & Bruno António Caetano Cardoso (with Belo, H.). 2015. PLoS ONE
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Artigo

The bone marrow-mediated protection of myeloproliferative neoplastic cells to vorinostat and ruxolitinib relies on the activation of JNK and PI3K Signalling Pathways

António de Almeida & Bruno António Caetano Cardoso (with Cardoso, B.A.). 2015. PLoS ONE
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Artigo

Validation of the revised international prognostic scoring system (IPSS-R) in patients with lower-risk myelodysplastic syndromes: a report from the prospective European LeukaemiaNet MDS (EUMDS) registry

António de Almeida (with de Swart, L.). 2015. British Journal of Haematology
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Artigo

Cell-type-specific transcriptional regulation of PIGM underpins the divergent hematologic phenotype in inherited GPl deficiency

António de Almeida (with Costa, J.R.). 2014. Blood
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Artigo

Optimizing treatments in rare diseases: Will our evidence come from registry data?

António de Almeida (with Almeida, A.M.). 2014. Leukemia Research
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Artigo

Efficacy and tolerability of 5-day azacytidine dose-intensified regimen in higher-risk MDS

António de Almeida (with Pierdomenico, F.). 2013. Annals of Hematology
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Artigo

Modifying disease in CMML: Who responds to Azacitidine?

António de Almeida (with Almeida, A.). 2013. Leukemia Research
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Artigo

Treatment of acute erythroleukemia with Azacitidine: A case series

António de Almeida (with Pierdomenico, F.). 2013. Leukemia Research Reports
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Artigo

Vorinostat Induces Apoptosis and Differentiation in Myeloid Malignancies: Genetic and Molecular Mechanisms

António de Almeida & Bruno António Caetano Cardoso (with Silva, G.). 2013. PLoS ONE
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Artigo

Generalized skin reactions in patients with MDS and CMML treated with azacitidine: Effective management with concomitant prednisolone

António de Almeida (with Almeida, A.M.). 2012. Leukemia Research
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Artigo

Treatment of chronic myelomonocytic leukemia with 5-Azacitidine: A case series and literature review

António de Almeida (with Thorpe, M.). 2012. Leukemia Research
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Artigo

Clinical management of gastrointestinal disturbances in patients with myelodysplastic syndromes receiving iron chelation treatment with deferasirox

António de Almeida (with Nolte, F.). 2011. Leukemia Research
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Artigo

Chapter 16 Inherited GPI deficiency

António de Almeida (with Almeida, A.). 2009. Enzymes
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Outras

Controlo transcricional de PIGM:mecanismo de expressão diferencial em células sanguíneas na insuficiência hereditária de GPI

António de Almeida (with Nolasco, Madalena Tavares Festas de Sousa). 2009.
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Artigo

Inherited glycosylphosphatidyl inositol deficiency: A treatable CDG

António de Almeida (with Almeida, A.). 2009. Biochimica et Biophysica Acta - Molecular Basis of Disease
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Artigo

Recommendations for diagnosis, treatment and monitoring of chronic myeloid leukemia | Recomendações para o diagnóstico, tratamento e monitorização da leucemia mielóide crónica

António de Almeida (with Almeida, A.). 2009. Acta Medica Portuguesa
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Artigo

Targeted therapy for inherited GPI deficiency

António de Almeida (with Almeida, A.M.). 2007. New England Journal of Medicine
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Artigo

Hypomorphic promoter mutation in PIGM causes inherited glycosylphosphatidylinositol deficiency

António de Almeida (with Almeida, A.M.). 2006. Nature Medicine
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Artigo

Regulation of hematopoiesis in vitro and in vivo by invariant NKT cells

António de Almeida (with Kotsianidis, I.). 2006. Blood
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Artigo

Bone involvement in sickle cell disease

António de Almeida (with Almeida, A.). 2005. British Journal of Haematology
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Artigo

Human invariant NKT cells are required for effective in vitro alloresponses

António de Almeida (with Patterson, S.). 2005. Journal of Immunology
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Artigo

Automated computer result reporting for haemoglobinopathy screening

António de Almeida (with Daniel, Y.). 2004. Clinical and Laboratory Haematology
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Artigo

Neonatal screening for sickle cell disorders

António de Almeida (with Henthorn, J.S.). 2004. British Journal of Haematology
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Artigo

The use of recombinant factor VIIa in children with inherited platelet function disorders.

António de Almeida 2003. British journal of haematology
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Artigo

Therapeutic challenges in childhood sickle cell disease Part 1: Current and future treatment options

António de Almeida (with Amrolia, P.J.). 2003. British Journal of Haematology
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Artigo

Therapeutic challenges in childhood sickle cell disease. Part 2: A problem-orientated approach

António de Almeida (with Amrolia, P.J.). 2003. British Journal of Haematology
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Artigo

Thromboprophylaxis with unmonitored intermediate-dose low molecular weight heparin in pregnancies with a previous arterial or venous thrombotic event.

António de Almeida (with Hunt, B.J.). 2003. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
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Artigo

Unusual presentation of factor XIII deficiency

António de Almeida (with Almeida, A.). 2002. Haemophilia
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Artigo

Fludarabine-based stem cell transplantation protocol for Fanconi's anaemia in myelodysplastic transformation

António de Almeida (with McCloy, M.). 2001. British Journal of Haematology
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Artigo

Neonatal screening for haemoglobinopathies: The results of a 10-year programme in an English Health Region

António de Almeida (with Almeida, A.M.). 2001. British Journal of Haematology
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