António de Almeida

Professor Catedrático

Generic Bio

Participação na FM-UCP

  • Diretor da Faculdade 
  • Mentor 

 

Áreas de Atividade

Hematologia Clínica | Anemia | Neoplasias Mieloides Crónicas | Epigenética | Educação Médica

 

Atividade Profissional

  • Faculdade de Medicina da Universidade Católica (FM-UCP) 
  • Centro de Investigação Interdisciplinar em Saúde (CIIS) – Plataforma CatólicaMed
  • Hospital da Luz Lisboa   

 

Formação

  • Universitdade: University of Cambridge 
  • Junho 1990: BA Hons (Cantab) 
  • Medical School: Addenbrooke's Hospital, Cambridge 
  • Dezembro 1993: MB Bchir (Cantab) 

 

Qualificações Pós-Graduação

  • Fevereiro 1997: MRCP (Lond) 
  • Setembro 2001: MRCPath 
  • Junho 2002: Certificado de conclusão de formação especializada (CCST) em Hematologia 
  • Maio 2007: PhD Imperial College 
  • Maio 2015: Consultor em Hematologia na Ordem dos Médicos 
  • Maio 2021: Agregação à Universidade Católica Portuguesa  

 

Resumo da Carreira Profissional

  • Janeiro 1993 – Set 1997: Interno geral, Cambridge e St George’s Hospital Londres
  • Setembro 1997 – Jun 2003: Interno especialidade hematologia Hospitais zona Norte de Londres (Hammersmith, Royal Free, Great Ormond Street, St Mary’s, Central Middlesex) 
  • Junho 2003 - Jun 2006: Leukaemia Research Fund Clinical Research Fellow 
  • Setembro 2006 – set 2017: Hematologista IPO Lisboa 
  • Setembro 2017 - Presente: Diretor de serviço de Hematologia, Hospital da Luz Lisboa 
  • Março 2021 - Presente: Diretor da Faculdade de Medicina da UCP 

 

Línguas

Português | Inglês | Italiano | Espanhol | Francês

 

Outros Interesses

  • O mais feliz no mar: barco ou surf 
  • Uso golf para estragar um bom passeio 
  • Fascínio por pássaros 
  • Boa comida e bebida 

 

Artigo

Automated identification of leukocyte subsets improves standardization of database-guided expert-supervised diagnostic orientation in acute leukemia: a EuroFlow study

António de Almeida (with Ludovic Lhermitte). 2021. Modern Pathology
Artigo

Outcomes of patients with chronic myelomonocytic leukaemia treated with non-curative therapies: a retrospective cohort study

António de Almeida (with Lisa Pleyer). 2021. The Lancet Haematology
Artigo

Phase III, Randomized, Placebo-Controlled Trial of CC-486 (Oral Azacitidine) in Patients With Lower-Risk Myelodysplastic Syndromes

António de Almeida (with Guillermo Garcia-Manero). 2021. Journal of Clinical Oncology
Artigo

Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia—From Molecular Mechanisms to Clinical Relevance

António de Almeida (with Raquel Alves). 2021. Cancers
Artigo

Spontaneous Tumor Lysis Syndrome: A Rare Presentation in Plasmablastic Lymphoma

António de Almeida (with Joana Infante). 2021. Journal of Hematology
Artigo

The Activation of Endothelial Cells Relies on a Ferroptosis-Like Mechanism: Novel Perspectives in Management of Angiogenesis and Cancer Therapy

António de Almeida (with Filipa Lopes-Coelho). 2021. Frontiers in Oncology
Artigo

Achievement of red blood cell transfusion independence in red blood cell transfusion-dependent patients with lower-risk non-del(5q) myelodysplastic syndromes correlates with serum erythropoietin levels.

António de Almeida 2020. Leukemia & lymphoma
Artigo

Guideline-based indicators for adult patients with myelodysplastic syndromes.

António de Almeida 2020. Blood advances
Artigo

Impact of somatic mutations on response to lenalidomide in lower-risk non-del(5q) myelodysplastic syndromes patients.

António de Almeida 2020. Leukemia
Artigo

Monocytes as Endothelial Progenitor Cells (EPCs), Another Brick in the Wall to Disentangle Tumor Angiogenesis.

António de Almeida 2020. Cells
Artigo

Novel dynamic outcome indicators and clinical endpoints in myelodysplastic syndrome; the European LeukemiaNet MDS Registry and MDS-RIGHT project perspective

António de Almeida (with Theo De Witte). 2020. Haematologica
Artigo

Oral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia in First Remission.

António de Almeida 2020. The New England journal of medicine
Artigo

Clinical Benefit-Risk Profile of Lenalidomide in Patients With Lower-risk Myelodysplastic Syndromes Without del(5q): Results of a Phase III Trial

António de Almeida (with Guillermo Garcia-Manero). 2019. Clinical Lymphoma Myeloma and Leukemia
Artigo

Everolimus in combination with Imatinib overcomes resistance in Chronic myeloid leukaemia.

António de Almeida 2019. Medical oncology (Northwood, London, England)
Artigo

Impact of treatment with iron chelation therapy in patients with lower-risk myelodysplastic syndromes participating in the European MDS registry.

António de Almeida 2019. Haematologica
Artigo

Less iron improves MDS haematopoiesis.

António de Almeida 2019. British journal of haematology
Artigo

Negative MR<sup>4·0</sup> chronic myeloid leukaemia and its possible implications for treatment-free remission.

António de Almeida 2019. British journal of haematology
Artigo

New prospects for the management of cardiovascular effects of tyrosine kinase inhibitors in patients with chronic myeloid leukemia.

António de Almeida 2019. Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
Artigo

Safety and efficacy findings from the open-label, multicenter, phase 3b, expanded treatment protocol study of ruxolitinib for treatment of patients with polycythemia vera who are resistant/intolerant to hydroxyurea and for whom no alternative treatme...

António de Almeida 2019. Leukemia & lymphoma
Artigo

Vorinostat synergizes with antioxidant therapy to target myeloproliferative neoplasms

António de Almeida & Bruno António Caetano Cardoso (with Cardoso, B.A.). 2019. Experimental Hematology
Artigo

Considerations for Treatment-free Remission in Patients With Chronic Myeloid Leukemia: A Joint Patient–Physician Perspective

António de Almeida (with Giuseppe Saglio). 2018. Clinical Lymphoma Myeloma and Leukemia
Artigo

Early platelet count kinetics has prognostic value in lower-risk myelodysplastic syndromes.

António de Almeida 2018. Blood advances
Artigo

Evaluation of induction chemotherapies after hypomethylating agent failure in myelodysplastic syndromes and acute myeloid leukemia.

António de Almeida 2018. Blood advances
Artigo

Evidence-Based Criteria for Tyrosine Kinase Inhibitor Interruption in Pregnancy.

António de Almeida 2018. Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Artigo

Hematology traning in Europe

António de Almeida (with A. Almeida). 2018. International Journal of Laboratory Hematology
Artigo

Should more MDS patients be treated with immune-suppression?

António de Almeida (with Antonio Almeida). 2018. Leukemia Research
Artigo

Clinical benefit of eculizumab in patients with no transfusion history in the International Paroxysmal Nocturnal Haemoglobinuria Registry

António de Almeida (with Almeida, A.M.). 2017. Internal Medicine Journal
Artigo

Clinical outcomes of 217 patients with acute erythroleukemia according to treatment type and line: A retrospective multinational study

António de Almeida (with Almeida, A.M.). 2017. International Journal of Molecular Sciences
Artigo

Clinical outcomes of AML patients treated with Azacitidine in Portugal: A retrospective multicenter study

António de Almeida (with Almeida, A.). 2017. Leukemia Research Reports
Artigo

Different clinical characteristics of paroxysmal nocturnal hemoglobinuria in pediatric and adult patients

António de Almeida (with Urbano-Ispizua, Á.). 2017. Haematologica
Artigo

HDAC8 overexpression in mesenchymal stromal cells from JAK2<sup>+</sup>myeloproliferative neoplasms: A new therapeutic target?

António de Almeida (with Ramos, T.L.). 2017. Oncotarget
Artigo

Real life experience with frontline azacitidine in a large series of older adults with acute myeloid leukemia stratified by MRC/LRF score: results from the expanded international E-ALMA series (E-ALMA+)

António de Almeida (with Falantes, J.). 2017. Leukemia and Lymphoma
Artigo

Recent advances in the treatment of lower-risk non-del(5q) myelodysplastic syndromes (MDS)

António de Almeida (with Almeida, A.). 2017. Leukemia Research
Artigo

Acute myeloid leukemia in the older adults

António de Almeida (with Almeida, A.M.). 2016. Leukemia Research Reports
Artigo

Design and rationale of the QUAZAR lower-risk MDS (AZA-MDS-003) trial: a randomized phase 3 study of CC-486 (oral azacitidine) plus best supportive care vs placebo plus best supportive care in patients with IPSS lower-risk myelodysplastic syndromes a...

António de Almeida (with Garcia-Manero, G.). 2016. BMC Hematology
Artigo

Design of the randomized, Phase III, QUAZAR AML Maintenance trial of CC-486 (oral azacitidine) maintenance therapy in acute myeloid leukemia

António de Almeida (with Roboz, G.J.). 2016. Future Oncology
Artigo

Randomized phase III study of lenalidomide versus placebo in RBC transfusion-dependent patients with lower-risk non-del(5q) myelodysplastic syndromes and ineligible for or refractory to erythropoiesis-stimulating agents

António de Almeida (with Santini, V.). 2016. Journal of Clinical Oncology
Artigo

Epigenetic Alterations in Fanconi anaemia: Role in pathophysiology and therapeutic potential

António de Almeida & Bruno António Caetano Cardoso (with Belo, H.). 2015. PLoS ONE
Artigo

The bone marrow-mediated protection of myeloproliferative neoplastic cells to vorinostat and ruxolitinib relies on the activation of JNK and PI3K Signalling Pathways

António de Almeida & Bruno António Caetano Cardoso (with Cardoso, B.A.). 2015. PLoS ONE
Artigo

Validation of the revised international prognostic scoring system (IPSS-R) in patients with lower-risk myelodysplastic syndromes: a report from the prospective European LeukaemiaNet MDS (EUMDS) registry

António de Almeida (with de Swart, L.). 2015. British Journal of Haematology
Artigo

Cell-type-specific transcriptional regulation of PIGM underpins the divergent hematologic phenotype in inherited GPl deficiency

António de Almeida (with Costa, J.R.). 2014. Blood
Artigo

Optimizing treatments in rare diseases: Will our evidence come from registry data?

António de Almeida (with Almeida, A.M.). 2014. Leukemia Research
Artigo

Efficacy and tolerability of 5-day azacytidine dose-intensified regimen in higher-risk MDS

António de Almeida (with Pierdomenico, F.). 2013. Annals of Hematology
Artigo

Modifying disease in CMML: Who responds to Azacitidine?

António de Almeida (with Almeida, A.). 2013. Leukemia Research
Artigo

Treatment of acute erythroleukemia with Azacitidine: A case series

António de Almeida (with Pierdomenico, F.). 2013. Leukemia Research Reports
Artigo

Vorinostat Induces Apoptosis and Differentiation in Myeloid Malignancies: Genetic and Molecular Mechanisms

António de Almeida & Bruno António Caetano Cardoso (with Silva, G.). 2013. PLoS ONE
Artigo

Generalized skin reactions in patients with MDS and CMML treated with azacitidine: Effective management with concomitant prednisolone

António de Almeida (with Almeida, A.M.). 2012. Leukemia Research
Artigo

Treatment of chronic myelomonocytic leukemia with 5-Azacitidine: A case series and literature review

António de Almeida (with Thorpe, M.). 2012. Leukemia Research
Artigo

Clinical management of gastrointestinal disturbances in patients with myelodysplastic syndromes receiving iron chelation treatment with deferasirox

António de Almeida (with Nolte, F.). 2011. Leukemia Research
Artigo

Chapter 16 Inherited GPI deficiency

António de Almeida (with Almeida, A.). 2009. Enzymes
Outras

Controlo transcricional de PIGM:mecanismo de expressão diferencial em células sanguíneas na insuficiência hereditária de GPI

António de Almeida (with Nolasco, Madalena Tavares Festas de Sousa). 2009.
Artigo

Inherited glycosylphosphatidyl inositol deficiency: A treatable CDG

António de Almeida (with Almeida, A.). 2009. Biochimica et Biophysica Acta - Molecular Basis of Disease
Artigo

Recommendations for diagnosis, treatment and monitoring of chronic myeloid leukemia | Recomendações para o diagnóstico, tratamento e monitorização da leucemia mielóide crónica

António de Almeida (with Almeida, A.). 2009. Acta Medica Portuguesa
Artigo

Targeted therapy for inherited GPI deficiency

António de Almeida (with Almeida, A.M.). 2007. New England Journal of Medicine
Artigo

Hypomorphic promoter mutation in PIGM causes inherited glycosylphosphatidylinositol deficiency

António de Almeida (with Almeida, A.M.). 2006. Nature Medicine
Artigo

Regulation of hematopoiesis in vitro and in vivo by invariant NKT cells

António de Almeida (with Kotsianidis, I.). 2006. Blood
Artigo

Bone involvement in sickle cell disease

António de Almeida (with Almeida, A.). 2005. British Journal of Haematology
Artigo

Human invariant NKT cells are required for effective in vitro alloresponses

António de Almeida (with Patterson, S.). 2005. Journal of Immunology
Artigo

Automated computer result reporting for haemoglobinopathy screening

António de Almeida (with Daniel, Y.). 2004. Clinical and Laboratory Haematology
Artigo

Neonatal screening for sickle cell disorders

António de Almeida (with Henthorn, J.S.). 2004. British Journal of Haematology
Artigo

The use of recombinant factor VIIa in children with inherited platelet function disorders.

António de Almeida 2003. British journal of haematology
Artigo

Therapeutic challenges in childhood sickle cell disease Part 1: Current and future treatment options

António de Almeida (with Amrolia, P.J.). 2003. British Journal of Haematology
Artigo

Therapeutic challenges in childhood sickle cell disease. Part 2: A problem-orientated approach

António de Almeida (with Amrolia, P.J.). 2003. British Journal of Haematology
Artigo

Thromboprophylaxis with unmonitored intermediate-dose low molecular weight heparin in pregnancies with a previous arterial or venous thrombotic event.

António de Almeida (with Hunt, B.J.). 2003. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Artigo

Unusual presentation of factor XIII deficiency

António de Almeida (with Almeida, A.). 2002. Haemophilia
Artigo

Fludarabine-based stem cell transplantation protocol for Fanconi's anaemia in myelodysplastic transformation

António de Almeida (with McCloy, M.). 2001. British Journal of Haematology
Artigo

Neonatal screening for haemoglobinopathies: The results of a 10-year programme in an English Health Region

António de Almeida (with Almeida, A.M.). 2001. British Journal of Haematology