Bruno António Caetano Cardoso

Professor Auxiliar

Generic Bio

Participação na FM-UCP

  • Coordenador da unidade curricular Crescimento e Desenvolvimento I 
  • Co-coordenador da unidade curricular Crescimento e Desenvolvimento II 
  • Aulas teóricas nas unidades curriculares Crescimento e Desenvolvimento I, Regulação e Integração e Crescimento e Desenvolvimento II
  • Tutor nas unidades curriculares Crescimento e Desenvolvimento I, Regulação e Integração e Crescimento e Desenvolvimento II
  • Mentor 

 

Áreas de Atividade

Biologia Celular e Molecular | Epigenética | Hemato-Oncologia 

 

Atividade Profissional

  • Faculdade de Medicina da Universidade Católica (FM-UCP) 
  • Centro de Investigação Interdisciplinar em Saúde (CIIS) – Plataforma CatólicaMed 

 

Formação 

  • 2005 - Licenciatura em Biologia Microbiana e Genética (Faculdade de Ciências da Universidade de Lisboa) 
  • 2011 - Doutoramento em Ciências Biomédicas (Faculdade de Medicina da Universidade de Lisboa)  

 

Resumo da Carreira Profissional

  • 2004 - 2005 – Estágio profissionalizante no Instituto de Medicina Molecular (IMM) – grupo de investigação do Prof. João Barata 
  • 2006 - 2011 – Estudante de Doutoramento no Instituto de Medicina Molecular (IMM) – grupo de investigação do Prof. João Barata 
  • 2012 – Pós-Doutoramento no Instituto de Medicina Molecular (IMM) – grupo de investigação do Prof. João Barata 
  • 2012 – 2016 - Pós-Doutoramento no Instituto Português de Oncologia de Lisboa (IPOL-FG)/Centro de Estudos de Doenças Crónicas (CEDOC) – grupo de investigação do Prof. António Almeida 
  • 2016 – 2018 - Pós-Doutoramento no Instituto de Medicina Molecular – João Lobo Antunes (IMM-JLA) – grupo de investigação do Prof. João Barata 
  • 2018 – 2021 – Investigador Sénior no Instituto de Medicina Molecular – João Lobo Antunes (IMM-JLA) – grupo de investigação do Prof. João Barata  

 

Línguas

Português | Inglês

 

Outros Interesses

  • Desporto
  • Política
  • História
  • Cinema  
Artigo

CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia

Bruno António Caetano Cardoso (with Bruno A. Cardoso). 2023. Haematologica
Artigo

Center for Interdisciplinary Research in Health (CIIS) National Meeting 2023

Bruno António Caetano Cardoso 2023. BMC Proceedings
Artigo

The Bone Marrow Niche - The Tumor Microenvironment That Ensures Leukemia Progression.

Bruno António Caetano Cardoso 2020. Advances in experimental medicine and biology
Artigo

Acetylation drives hepatocyte nuclear factor 1β stability by blocking proteasome-mediated degradation

Bruno António Caetano Cardoso (with Lopes-Coelho, F.). 2019. Journal of Cellular Biochemistry
Artigo

Vorinostat synergizes with antioxidant therapy to target myeloproliferative neoplasms

António de Almeida & Bruno António Caetano Cardoso (with Cardoso, B.A.). 2019. Experimental Hematology
Artigo

STAT5 is essential for IL-7–mediated viability, growth, and proliferation of T-cell acute lymphoblastic leukemia cells

Bruno António Caetano Cardoso (with Daniel Ribeiro). 2018. Blood Advances
Artigo

From the outside, from within: Biological and therapeutic relevance of signal transduction in T-cell acute lymphoblastic leukemia

Bruno António Caetano Cardoso (with Oliveira, M.L.). 2017. Cellular Signalling
Artigo

RAC1b overexpression stimulates proliferation and NF-κB-mediated antiapoptotic signaling in thyroid cancer cells

Bruno António Caetano Cardoso (with Faria, M.). 2017. PLoS ONE
Artigo

FOXP3 can modulate TAL1 transcriptional activity through interaction with LMO2

Bruno António Caetano Cardoso (with Fleskens, V.). 2016. Oncogene
Artigo

Optimal interleukin-7 receptor-mediated signaling, cell cycle progression and viability of t-cell acute lymphoblastic leukemia cells rely on casein kinase 2 activity

Bruno António Caetano Cardoso (with Melão, A.). 2016. Haematologica
Artigo

Epigenetic Alterations in Fanconi anaemia: Role in pathophysiology and therapeutic potential

António de Almeida & Bruno António Caetano Cardoso (with Belo, H.). 2015. PLoS ONE
Artigo

PI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemia

Bruno António Caetano Cardoso (with Silveira, A.B.). 2015. Oncotarget
Artigo

The bone marrow-mediated protection of myeloproliferative neoplastic cells to vorinostat and ruxolitinib relies on the activation of JNK and PI3K Signalling Pathways

António de Almeida & Bruno António Caetano Cardoso (with Cardoso, B.A.). 2015. PLoS ONE
Artigo

Activity of the clinical-stage CK2-specific inhibitor CX-4945 against chronic lymphocytic leukemia

Bruno António Caetano Cardoso (with Martins, L.R.). 2014. Leukemia
Artigo

Vorinostat Induces Apoptosis and Differentiation in Myeloid Malignancies: Genetic and Molecular Mechanisms

António de Almeida & Bruno António Caetano Cardoso (with Silva, G.). 2013. PLoS ONE
Outras

IL-4 and TAL1 in T-cell acute lymphoblastic leukemia : studies on the participation of microenvironmental cues and cell-autonomous alterations in leukemogenesis

Bruno António Caetano Cardoso (with Cardoso, Bruno António Caetano, 1982-). 2011.
Artigo

IL-7 contributes to the progression of human T-cell acute lymphoblastic leukemias

Bruno António Caetano Cardoso (with Silva, A.). 2011. Cancer Research
Artigo

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

Bruno António Caetano Cardoso (with Zenatti, P.P.). 2011. Nature Genetics
Artigo

TAL1/SCL is downregulated upon histone deacetylase inhibition in T-cell acute lymphoblastic leukemia cells

Bruno António Caetano Cardoso (with Cardoso, B.A.). 2011. Leukemia
Artigo

Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human γδ T-cells

Bruno António Caetano Cardoso (with Correia, D.V.). 2009. PLoS ONE
Artigo

Interleukin-4 stimulates proliferation and growth of T-cell acute lymphoblastic leukemia cells by activating mTOR signaling

Bruno António Caetano Cardoso (with Cardoso, B.A.). 2009. Leukemia
Artigo

Aberrant signaling in T-cell acute lymphoblastic leukemia: Biological and therapeutic implications

Bruno António Caetano Cardoso (with Cardoso, B.A.). 2008. Brazilian Journal of Medical and Biological Research
Artigo

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

Bruno António Caetano Cardoso (with Silva, A.). 2008. Journal of Clinical Investigation