Curricular Units – 1st Semester

Physiological Basis of Sleep

Theories about sleep functions

Adaptations of bodily Functions of sleep

Physiological Basis of Sleep

• Effects of acute and chronic sleep deprivation
• Sleep and dreaming
• Gender differences in sleep
• Sleep, Mind and Gut
• The neurophysiology and neurobiology of wakefulness NREM sleep, and paradoxical or REM sleep

Sleep Disorders I and Diagnostic Procedures I

Classification of sleep disorders

The clinical interview and the objective examination

Sleep Lab I

Sleep exams (adult and children): sleep staging, scoring of events

Other exams

Disturbances of Sleep I

Insomnia

• Nosological classification, definitions, and epidemiology
• Pathophysiology
• Clinical picture and diagnosis
• Comorbidities and special populations
• Treatment: Current guidelines; Cognitive behavioral therapy for insomnia and other psychotherapeutic approaches; Pharmacological treatment; Evidence-based efficacy of alternative interventions

Sleep and Psychiatry

Disturbances of Sleep II

Hypersomnias of Central origin

• Nosological classification, definitions, and epidemiology
• Pathophysiology
• Clinical picture and diagnosis
• Treatment

Parasomnias

• Nosological classification, definitions, and epidemiology
• Pathophysiology and Psychopathology
• Clinical findings
• Special populations and comorbidities
• Treatment

Sleep related movement disorders

• Nosological classification, definitions, and epidemiology
• Pathophysiology and Psychopathology
• Clinical findings
• Comorbidities
• Treatment

Sleep and Neurology

• Epilepsy, Parkinsonian Syndromes, Dementias, Stroke, Headache, Multiple sclerosis and other autoimmune disorders, neuromuscular disorders

Disturbances of Sleep III

Sleep related respiratory disorders

• Nosological classification, definitions, and epidemiology
• Pathophysiology and Psychopathology
• Clinical picture and diagnosis
• Obstructive sleep apnea and comorbidities: A specific focus on cardiometabolic comorbidities
• Treatment

Sleep and Pneumology

• Overview and pathophysiology
• Obstructive sleep apnea and chronic obstructive pulmonary disease overlap
• Sleep-disordered breathing and asthma
• Sleep-disordered breathing and Interstitial Lung Disease
• Hypoventilation disorders

Disturbances of Sleep IV

Circadian rhythm sleep disorders

• Nosological classification, definitions, and epidemiology
• Pathophysiology

Shift Work
Delayed sleep-wake phase disorder
Non-24-hour sleep-wake disorder

• Clinical picture and diagnosis
• Comorbidities
• Health risks
• Treatment

Sleep in Pediatric Ages

Disturbances of sleep in pediatric ages

• Chronic insomnia
• Specific features of parasomnias
• Obstructive sleep apnea
• Sleep-related movement disorders
• Narcolepsy
• Sleep in neurodevelopmental disorders
• Sleep and academic performance

Sleep studies in pediatric ages

Dental Sleep Medicine I

• Clinical documentation
• Anamneses and Screening in Dental Sleep Medicine 
• Patients’ clinical evaluation
• Radiology and Upper Airway evaluation
• Role of Orthodontics on treatment and management of Obstructive Sleep Apnea (OSA)
• Functional orthopedic of the Jaws on the dimension and treatment of the Upper airway
• Temporomandibular Joint clinical evaluation
• COAT-Continue Opening Airway Therapy 
• Oral Comorbidities on OSA
• Sleep Bruxism 
• Pediatric Sleep -
• Orthognathic Treatment
• Hypoglossal Nerve Stimulation
• Combined Therapy CPAP-Mandibular Advance Device

Sleep and other medical specialties

• Sleep and nutrition
• Sleep and cancer
• Sleep and pharmacology
• Sleep and acupuncture
• Sleep and Aesthetic Medicine

Sleep, Research and Clinical Practice

• Sleep and research
• Sleep in clinical practice

Practical component

• Adult polysomnography analysis: sleep staging, analysis of respiratory and movement events
• Pediatric polysomnography analysis: sleep staging, analysis of respiratory and movement events
• Non-invasive ventilation (NIV): adaptation of NIV in patients with sleep related respiratory perturbances
• Multiple sleep latency test and vigilance maintenance test: clinical cases
• Actigraphy
• Meet the Expert in Sleep Lab

Curricular Units – 2^nd Semester

Diagnostic Procedures II

Biological fluids and Biomarkers

Drug induced sleep endoscopy (DISE)

Cephalometric analysis and Evaluation of Upperway

Sleep Lab II

Sleep exams (adult and children): sleep staging, scoring of events

Other exams: MSLT (multiple sleep latency test), MWT (maintenance wakefulness test), actigraphy, oximetry, and respiratory function tests

Epilepsy, Parasomnias and PSG (polisomnography)

Non-invasive ventilation (NIV): adaptation of NIV in patients with sleep related respiratory perturbances

Interpretation of sleep exams

Sleep Disorders II and Therapeutic Approaches

Hot topics about sleep disorders: from diagnosis to treatment

Sleep in specific populations: sleep in competetion athletes, genetic syndromes, pregnancy

Specific approaches to sleep disorders: orthodontics, myofunctional therapy, Cognitive behavior therapy, hypoglossal nerve stimulation, non-invasive ventilation, surgery

Clinical Practice

Discussion of clinical cases

Dental Sleep Medicine II

Myofunctional Therapy and Myofunctional devices

Occlusal registration bite with George Gauge and Intra-oral impressions (silicone or scanner)

Delivery and Mandibular advancement device (MAD) adjustments

Cephalometric Analysis and Evaluation of the Upper airway

DISE as an evaluation method of Upper airway and DAM titulation

Orofacial pain and Sleep

Maxilo-mandibular Surgery approach in OSA

Management of Marpe & Baume and UAW outcomes

Meet the Expert

Seminars

Oral presentation of a review or an original work