Bruno António Caetano Cardoso

Assistant Professor
Bruno Caetano Cardoso

bacardoso@ucp.pt

Generic Bio

Participation in Católica Medical School

  • Coordinator of the curricular unit Growth and Development I 
  • Co-coordinator of curricular unit Growth and Development II 
  • Lectures in curricular units Growth and Development I, Regulation and Integration and Growth and Development II
  • Tutor in curricular units Growth and Development I, Regulation and Integration and Growth and Development II
  • Mentor 
     

Field of Work

Cell and Molecular Biology | Epigenetics | Hemato-Oncology 

 

Professional Activity

  • Católica Medical School (FM-UCP) 
  • Centre for Interdisciplinary Research in Health (CIIS) - CatólicaMed Platform 
     

Education 

  • 2005 - Licentiate Degree in Microbial Biology and Genetics (Faculty of Sciences of the University of Lisbon) 
  • 2011 - PhD in Biomedical Sciences (Faculty of Medicine of the University of Lisbon)  


Summary of Professional Career

  • 2004 - 2005 - Internship at the Institute of Molecular Medicine (IMM) - research group of Prof. João Barata 
  • 2006 - 2011 - PhD student at the Instituto de Medicina Molecular (IMM) - research group of Prof. João Barata 
  • 2012 - Postdoctoral fellow at the Instituto de Medicina Molecular (IMM) - research group of Prof. João Barata 
  • 2012 - 2016 - Postdoctoral fellowship at the Portuguese Institute of Oncology of Lisbon (IPOL-FG)/Centre for Chronic Disease Studies (CEDOC) - research group of Prof. António Almeida 
  • 2016 - 2018 - Postdoctoral researcher at the Institute of Molecular Medicine - João Lobo Antunes (IMM-JLA) - research group of Prof. João Barata 
  • 2018 - 2021 - Senior Researcher at the Institute of Molecular Medicine - João Lobo Antunes (IMM-JLA) - research group of Prof. João Barata  


Languages

Portuguese | English

 

Other Interests

  • Sports
  • Politics
  • History
  • Cinema  
Programs:
Modules / Courses:
Paper

Immune-monitoring of myelodysplastic neoplasms

Bruno António Caetano Cardoso (with i4MDS consortium). 2024. HemaSphere
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Paper

CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia

Bruno António Caetano Cardoso (with Bruno A. Cardoso). 2023. Haematologica
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Paper

Center for Interdisciplinary Research in Health (CIIS) National Meeting 2023

Bruno António Caetano Cardoso 2023. BMC Proceedings
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Paper

The Bone Marrow Niche - The Tumor Microenvironment That Ensures Leukemia Progression.

Bruno António Caetano Cardoso 2020. Advances in experimental medicine and biology
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Paper

Acetylation drives hepatocyte nuclear factor 1β stability by blocking proteasome-mediated degradation

Bruno António Caetano Cardoso (with Lopes-Coelho, F.). 2019. Journal of Cellular Biochemistry
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Paper

Vorinostat synergizes with antioxidant therapy to target myeloproliferative neoplasms

António Almeida & Bruno António Caetano Cardoso (with Cardoso, B.A.). 2019. Experimental Hematology
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Paper

STAT5 is essential for IL-7–mediated viability, growth, and proliferation of T-cell acute lymphoblastic leukemia cells

Bruno António Caetano Cardoso (with Daniel Ribeiro). 2018. Blood Advances
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Paper

From the outside, from within: Biological and therapeutic relevance of signal transduction in T-cell acute lymphoblastic leukemia

Bruno António Caetano Cardoso (with Oliveira, M.L.). 2017. Cellular Signalling
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Paper

RAC1b overexpression stimulates proliferation and NF-κB-mediated antiapoptotic signaling in thyroid cancer cells

Bruno António Caetano Cardoso (with Faria, M.). 2017. PLoS ONE
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Paper

FOXP3 can modulate TAL1 transcriptional activity through interaction with LMO2

Bruno António Caetano Cardoso (with Fleskens, V.). 2016. Oncogene
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Paper

Optimal interleukin-7 receptor-mediated signaling, cell cycle progression and viability of t-cell acute lymphoblastic leukemia cells rely on casein kinase 2 activity

Bruno António Caetano Cardoso (with Melão, A.). 2016. Haematologica
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Paper

Epigenetic Alterations in Fanconi anaemia: Role in pathophysiology and therapeutic potential

António Almeida & Bruno António Caetano Cardoso (with Belo, H.). 2015. PLoS ONE
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Paper

PI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemia

Bruno António Caetano Cardoso (with Silveira, A.B.). 2015. Oncotarget
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Paper

The bone marrow-mediated protection of myeloproliferative neoplastic cells to vorinostat and ruxolitinib relies on the activation of JNK and PI3K Signalling Pathways

António Almeida & Bruno António Caetano Cardoso (with Cardoso, B.A.). 2015. PLoS ONE
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Paper

Activity of the clinical-stage CK2-specific inhibitor CX-4945 against chronic lymphocytic leukemia

Bruno António Caetano Cardoso (with Martins, L.R.). 2014. Leukemia
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Paper

Vorinostat Induces Apoptosis and Differentiation in Myeloid Malignancies: Genetic and Molecular Mechanisms

António Almeida & Bruno António Caetano Cardoso (with Silva, G.). 2013. PLoS ONE
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Other

IL-4 and TAL1 in T-cell acute lymphoblastic leukemia : studies on the participation of microenvironmental cues and cell-autonomous alterations in leukemogenesis

Bruno António Caetano Cardoso (with Cardoso, Bruno António Caetano, 1982-). 2011.
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Paper

IL-7 contributes to the progression of human T-cell acute lymphoblastic leukemias

Bruno António Caetano Cardoso (with Silva, A.). 2011. Cancer Research
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Paper

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

Bruno António Caetano Cardoso (with Zenatti, P.P.). 2011. Nature Genetics
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Paper

TAL1/SCL is downregulated upon histone deacetylase inhibition in T-cell acute lymphoblastic leukemia cells

Bruno António Caetano Cardoso (with Cardoso, B.A.). 2011. Leukemia
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Paper

Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human γδ T-cells

Bruno António Caetano Cardoso (with Correia, D.V.). 2009. PLoS ONE
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Paper

Interleukin-4 stimulates proliferation and growth of T-cell acute lymphoblastic leukemia cells by activating mTOR signaling

Bruno António Caetano Cardoso (with Cardoso, B.A.). 2009. Leukemia
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Paper

Aberrant signaling in T-cell acute lymphoblastic leukemia: Biological and therapeutic implications

Bruno António Caetano Cardoso (with Cardoso, B.A.). 2008. Brazilian Journal of Medical and Biological Research
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Paper

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

Bruno António Caetano Cardoso (with Silva, A.). 2008. Journal of Clinical Investigation
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