António Almeida

Full Professor

Generic Bio

Participation in Católica Medical School 

  • Founding Dean
  • Mentor 

 

Field of Work

Clinical Hematology | Anemia | Chronic Myeloid Neoplasms | Epigenetics | Medical Education 

 

Profissional Activity

  • Dean of the Católica Medical School (FM-UCP) 
  • Centro de Investigação Interdisciplinar em Saúde (CIIS) – CatólicaMed Platform
  • Hospital da Luz Lisboa   

 

Education

  • University: University of Cambridge 
  • June 1990: BA Hons (Cantab) 
  • Medical School: Addenbrooke's Hospital, Cambridge 
  • December 1993: MB Bchir (Cantab) 

 

Postgraduate qualifications

  • Februrary 1997: MRCP (Lond) 
  • September 2001: MRCPath 
  • June 2002: Certificate of completion of specialist training (CCST) in Haematology 
  • May 2007: PhD Imperial College 
  • May 2015: Consultant in Hematology Ordem dos Médicos  
  • May 2021: Aggregation Universidade Católica Portuguesa  

 

Professional Career

  • January 1993 – September 1997: General Intern, Cambridge and St George’s Hospital London
  • September 1997 – June 2003: Intern speciality Haematology at North London Hospitals (Hammersmith, Royal Free, Great Ormond Street, St Mary’s, Central Middlesex) 
  • June 2003 - June 2006: Leukaemia Research Fund Clinical Research Fellow 
  • September 2006 – September 2017: Haematologist IPO Lisboa 
  • September 2017 - Now: Head of Haematology Service, Hospital da Luz Lisboa 
  • March 2021 - Now: Dean of the Católica Medical School

 

Languages

Portuguese| English | Italian | Spanish| French

 

Other Interests

  • The happiest at sea: boating or surfing 
  • I use golf to spoil a good outing 
  • Fascination with birds 
  • Good food and drink 

 

Paper

Automated identification of leukocyte subsets improves standardization of database-guided expert-supervised diagnostic orientation in acute leukemia: a EuroFlow study

António Almeida (with Ludovic Lhermitte). 2021. Modern Pathology
Paper

Outcomes of patients with chronic myelomonocytic leukaemia treated with non-curative therapies: a retrospective cohort study

António Almeida (with Lisa Pleyer). 2021. The Lancet Haematology
Paper

Phase III, Randomized, Placebo-Controlled Trial of CC-486 (Oral Azacitidine) in Patients With Lower-Risk Myelodysplastic Syndromes

António Almeida (with Guillermo Garcia-Manero). 2021. Journal of Clinical Oncology
Paper

Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia—From Molecular Mechanisms to Clinical Relevance

António Almeida (with Raquel Alves). 2021. Cancers
Paper

Spontaneous Tumor Lysis Syndrome: A Rare Presentation in Plasmablastic Lymphoma

António Almeida (with Joana Infante). 2021. Journal of Hematology
Paper

The Activation of Endothelial Cells Relies on a Ferroptosis-Like Mechanism: Novel Perspectives in Management of Angiogenesis and Cancer Therapy

António Almeida (with Filipa Lopes-Coelho). 2021. Frontiers in Oncology
Paper

Achievement of red blood cell transfusion independence in red blood cell transfusion-dependent patients with lower-risk non-del(5q) myelodysplastic syndromes correlates with serum erythropoietin levels.

António Almeida 2020. Leukemia & lymphoma
Paper

Guideline-based indicators for adult patients with myelodysplastic syndromes.

António Almeida 2020. Blood advances
Paper

Impact of somatic mutations on response to lenalidomide in lower-risk non-del(5q) myelodysplastic syndromes patients.

António Almeida 2020. Leukemia
Paper

Monocytes as Endothelial Progenitor Cells (EPCs), Another Brick in the Wall to Disentangle Tumor Angiogenesis.

António Almeida 2020. Cells
Paper

Novel dynamic outcome indicators and clinical endpoints in myelodysplastic syndrome; the European LeukemiaNet MDS Registry and MDS-RIGHT project perspective

António Almeida (with Theo De Witte). 2020. Haematologica
Paper

Oral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia in First Remission.

António Almeida 2020. The New England journal of medicine
Paper

Clinical Benefit-Risk Profile of Lenalidomide in Patients With Lower-risk Myelodysplastic Syndromes Without del(5q): Results of a Phase III Trial

António Almeida (with Guillermo Garcia-Manero). 2019. Clinical Lymphoma Myeloma and Leukemia
Paper

Everolimus in combination with Imatinib overcomes resistance in Chronic myeloid leukaemia.

António Almeida 2019. Medical oncology (Northwood, London, England)
Paper

Impact of treatment with iron chelation therapy in patients with lower-risk myelodysplastic syndromes participating in the European MDS registry.

António Almeida 2019. Haematologica
Paper

Less iron improves MDS haematopoiesis.

António Almeida 2019. British journal of haematology
Paper

Negative MR<sup>4·0</sup> chronic myeloid leukaemia and its possible implications for treatment-free remission.

António Almeida 2019. British journal of haematology
Paper

New prospects for the management of cardiovascular effects of tyrosine kinase inhibitors in patients with chronic myeloid leukemia.

António Almeida 2019. Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
Paper

Safety and efficacy findings from the open-label, multicenter, phase 3b, expanded treatment protocol study of ruxolitinib for treatment of patients with polycythemia vera who are resistant/intolerant to hydroxyurea and for whom no alternative treatme...

António Almeida 2019. Leukemia & lymphoma
Paper

Vorinostat synergizes with antioxidant therapy to target myeloproliferative neoplasms

António Almeida & Bruno António Caetano Cardoso (with Cardoso, B.A.). 2019. Experimental Hematology
Paper

Considerations for Treatment-free Remission in Patients With Chronic Myeloid Leukemia: A Joint Patient–Physician Perspective

António Almeida (with Giuseppe Saglio). 2018. Clinical Lymphoma Myeloma and Leukemia
Paper

Early platelet count kinetics has prognostic value in lower-risk myelodysplastic syndromes.

António Almeida 2018. Blood advances
Paper

Evaluation of induction chemotherapies after hypomethylating agent failure in myelodysplastic syndromes and acute myeloid leukemia.

António Almeida 2018. Blood advances
Paper

Evidence-Based Criteria for Tyrosine Kinase Inhibitor Interruption in Pregnancy.

António Almeida 2018. Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Paper

Hematology traning in Europe

António Almeida (with A. Almeida). 2018. International Journal of Laboratory Hematology
Paper

Should more MDS patients be treated with immune-suppression?

António Almeida (with Antonio Almeida). 2018. Leukemia Research
Paper

Clinical benefit of eculizumab in patients with no transfusion history in the International Paroxysmal Nocturnal Haemoglobinuria Registry

António Almeida (with Almeida, A.M.). 2017. Internal Medicine Journal
Paper

Clinical outcomes of 217 patients with acute erythroleukemia according to treatment type and line: A retrospective multinational study

António Almeida (with Almeida, A.M.). 2017. International Journal of Molecular Sciences
Paper

Clinical outcomes of AML patients treated with Azacitidine in Portugal: A retrospective multicenter study

António Almeida (with Almeida, A.). 2017. Leukemia Research Reports
Paper

Different clinical characteristics of paroxysmal nocturnal hemoglobinuria in pediatric and adult patients

António Almeida (with Urbano-Ispizua, Á.). 2017. Haematologica
Paper

HDAC8 overexpression in mesenchymal stromal cells from JAK2<sup>+</sup>myeloproliferative neoplasms: A new therapeutic target?

António Almeida (with Ramos, T.L.). 2017. Oncotarget
Paper

Real life experience with frontline azacitidine in a large series of older adults with acute myeloid leukemia stratified by MRC/LRF score: results from the expanded international E-ALMA series (E-ALMA+)

António Almeida (with Falantes, J.). 2017. Leukemia and Lymphoma
Paper

Recent advances in the treatment of lower-risk non-del(5q) myelodysplastic syndromes (MDS)

António Almeida (with Almeida, A.). 2017. Leukemia Research
Paper

Acute myeloid leukemia in the older adults

António Almeida (with Almeida, A.M.). 2016. Leukemia Research Reports
Paper

Design and rationale of the QUAZAR lower-risk MDS (AZA-MDS-003) trial: a randomized phase 3 study of CC-486 (oral azacitidine) plus best supportive care vs placebo plus best supportive care in patients with IPSS lower-risk myelodysplastic syndromes a...

António Almeida (with Garcia-Manero, G.). 2016. BMC Hematology
Paper

Design of the randomized, Phase III, QUAZAR AML Maintenance trial of CC-486 (oral azacitidine) maintenance therapy in acute myeloid leukemia

António Almeida (with Roboz, G.J.). 2016. Future Oncology
Paper

Randomized phase III study of lenalidomide versus placebo in RBC transfusion-dependent patients with lower-risk non-del(5q) myelodysplastic syndromes and ineligible for or refractory to erythropoiesis-stimulating agents

António Almeida (with Santini, V.). 2016. Journal of Clinical Oncology
Paper

Epigenetic Alterations in Fanconi anaemia: Role in pathophysiology and therapeutic potential

António Almeida & Bruno António Caetano Cardoso (with Belo, H.). 2015. PLoS ONE
Paper

The bone marrow-mediated protection of myeloproliferative neoplastic cells to vorinostat and ruxolitinib relies on the activation of JNK and PI3K Signalling Pathways

António Almeida & Bruno António Caetano Cardoso (with Cardoso, B.A.). 2015. PLoS ONE
Paper

Validation of the revised international prognostic scoring system (IPSS-R) in patients with lower-risk myelodysplastic syndromes: a report from the prospective European LeukaemiaNet MDS (EUMDS) registry

António Almeida (with de Swart, L.). 2015. British Journal of Haematology
Paper

Cell-type-specific transcriptional regulation of PIGM underpins the divergent hematologic phenotype in inherited GPl deficiency

António Almeida (with Costa, J.R.). 2014. Blood
Paper

Optimizing treatments in rare diseases: Will our evidence come from registry data?

António Almeida (with Almeida, A.M.). 2014. Leukemia Research
Paper

Efficacy and tolerability of 5-day azacytidine dose-intensified regimen in higher-risk MDS

António Almeida (with Pierdomenico, F.). 2013. Annals of Hematology
Paper

Modifying disease in CMML: Who responds to Azacitidine?

António Almeida (with Almeida, A.). 2013. Leukemia Research
Paper

Treatment of acute erythroleukemia with Azacitidine: A case series

António Almeida (with Pierdomenico, F.). 2013. Leukemia Research Reports
Paper

Vorinostat Induces Apoptosis and Differentiation in Myeloid Malignancies: Genetic and Molecular Mechanisms

António Almeida & Bruno António Caetano Cardoso (with Silva, G.). 2013. PLoS ONE
Paper

Generalized skin reactions in patients with MDS and CMML treated with azacitidine: Effective management with concomitant prednisolone

António Almeida (with Almeida, A.M.). 2012. Leukemia Research
Paper

Treatment of chronic myelomonocytic leukemia with 5-Azacitidine: A case series and literature review

António Almeida (with Thorpe, M.). 2012. Leukemia Research
Paper

Clinical management of gastrointestinal disturbances in patients with myelodysplastic syndromes receiving iron chelation treatment with deferasirox

António Almeida (with Nolte, F.). 2011. Leukemia Research
Paper

Chapter 16 Inherited GPI deficiency

António Almeida (with Almeida, A.). 2009. Enzymes
Other

Controlo transcricional de PIGM:mecanismo de expressão diferencial em células sanguíneas na insuficiência hereditária de GPI

António Almeida (with Nolasco, Madalena Tavares Festas de Sousa). 2009.
Paper

Inherited glycosylphosphatidyl inositol deficiency: A treatable CDG

António Almeida (with Almeida, A.). 2009. Biochimica et Biophysica Acta - Molecular Basis of Disease
Paper

Recommendations for diagnosis, treatment and monitoring of chronic myeloid leukemia | Recomendações para o diagnóstico, tratamento e monitorização da leucemia mielóide crónica

António Almeida (with Almeida, A.). 2009. Acta Medica Portuguesa
Paper

Targeted therapy for inherited GPI deficiency

António Almeida (with Almeida, A.M.). 2007. New England Journal of Medicine
Paper

Hypomorphic promoter mutation in PIGM causes inherited glycosylphosphatidylinositol deficiency

António Almeida (with Almeida, A.M.). 2006. Nature Medicine
Paper

Regulation of hematopoiesis in vitro and in vivo by invariant NKT cells

António Almeida (with Kotsianidis, I.). 2006. Blood
Paper

Bone involvement in sickle cell disease

António Almeida (with Almeida, A.). 2005. British Journal of Haematology
Paper

Human invariant NKT cells are required for effective in vitro alloresponses

António Almeida (with Patterson, S.). 2005. Journal of Immunology
Paper

Automated computer result reporting for haemoglobinopathy screening

António Almeida (with Daniel, Y.). 2004. Clinical and Laboratory Haematology
Paper

Neonatal screening for sickle cell disorders

António Almeida (with Henthorn, J.S.). 2004. British Journal of Haematology
Paper

The use of recombinant factor VIIa in children with inherited platelet function disorders.

António Almeida 2003. British journal of haematology
Paper

Therapeutic challenges in childhood sickle cell disease Part 1: Current and future treatment options

António Almeida (with Amrolia, P.J.). 2003. British Journal of Haematology
Paper

Therapeutic challenges in childhood sickle cell disease. Part 2: A problem-orientated approach

António Almeida (with Amrolia, P.J.). 2003. British Journal of Haematology
Paper

Thromboprophylaxis with unmonitored intermediate-dose low molecular weight heparin in pregnancies with a previous arterial or venous thrombotic event.

António Almeida (with Hunt, B.J.). 2003. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Paper

Unusual presentation of factor XIII deficiency

António Almeida (with Almeida, A.). 2002. Haemophilia
Paper

Fludarabine-based stem cell transplantation protocol for Fanconi's anaemia in myelodysplastic transformation

António Almeida (with McCloy, M.). 2001. British Journal of Haematology
Paper

Neonatal screening for haemoglobinopathies: The results of a 10-year programme in an English Health Region

António Almeida (with Almeida, A.M.). 2001. British Journal of Haematology