Inês Milagre

Assistant Professor
I Milagre

Bio

Participation in Católica Medical School 

  • Tutor in blocks 1.1 and 2.2
  • Tutor in the second-year elective of the Integrated Master in Medicine Introduction to Biomedical Research

Field of Work

Pluripotent cells | Reprogramming | Aging | Epigenetics | Medical Education

Profissional Activity

  • Católica Medical School (CMS)
  • Católica Biomedical Research Centre (CBR)

Education

  • PhD: Faculty of Pharmacy, University of Lisbon
  • Bachelor's degree: Faculty of Sciences, University of Lisbon

Professional Career

  • 2022-Present: Assistant Professor at the Faculty of Medicine, UCP 
  • 2022-Present: Research scientist at Católica Biomedical Research Centre (CBR)
  • Postdoctoral fellowship 2016-2022: Gulbenkian Institute of Science (Marie Skłodowska-Curie Fellowship and FCT contract)
  • Postdoctoral fellowship 2011-2016: Babraham Institute - Cambridge, UK (FEBS Fellowship and Epigenesys contract)

Languages

Portuguese | English

Other Interesses

  • Travel
  • Photography
  • Books

 

Other

Removal of nascent transcripts by TTF2 is required for sister chromatid resolution in human cells

Raquel Oliveira & Inês Milagre (with Laura Tovini). 2026.
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Other

Common mechanistic pathways in rare congenital syndromes with primary microcephaly

Raquel Oliveira & Inês Milagre (with Jorge, Xavier). 2025. Medicine (United States)
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Paper

Compromised Mitotic Fidelity in Human Pluripotent Stem Cells

Raquel Oliveira & Inês Milagre (with Milagre, Inês). 2023. International Journal of Molecular Sciences
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Other

Understanding mitotic physiology of pluripotent stem cells

Inês Milagre (with Pereira, Carolina). 2023. EMBO Young Scientists' Fórum
Paper

Generation and characterization of induced pluripotent stem cell line (IBBISTi004-A) from an Angelman syndrome patient carrying a class II deletion of the maternal chromosome 15q11.2-q13

Inês Milagre 2022. Stem Cell Research
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Paper

Multi-omic rejuvenation of human cells by maturation phase transient reprogramming

Inês Milagre (with Diljeet Gill). 2022. eLife
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Paper

Voicing the need to consider sex-specific differences in research

Inês Milagre (with Irene Miguel-Aliaga). 2022. Developmental Cell
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Paper

Generation and characterization of induced pluripotent stem cells from a family carrying the BRCA1 mutation c.3612delA

Inês Milagre 2021. Stem Cell Research
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Paper

Generation and characterization of induced pluripotent stem cells heterozygous for the Portuguese BRCA2 founder mutation.

Inês Milagre 2021. Stem cell research
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Other

Multi-omic rejuvenation of human cells by maturation phase transient reprogramming

Inês Milagre (with Diljeet Gill). 2021.
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Other

Novel Reprogramming Method

Inês Milagre 2021.
Other

Reprogramming of Human Fibroblasts to Pluripotency Induces CENP-A Chromatin Depletion

Inês Milagre (with Milagre, INÊS). 2021. ISSCR 2021 anual meeting
Other

Generation of patient-derived iPSCs for disease modelling

Inês Milagre (with da Rocha, Simão T.). 2020. EATRIS Annual Meeting
Other

iPSC-derived mammary organoids as a model to study the onset of malignant transformation triggered by BRCA mutations

Inês Milagre (with Pereira da Silva, Teresa). 2020. EMBO Symposium on Organoids: Modelling Organ Development and Disease in 3D Culture
Other

Reprogramming of Human Cells to Pluripotency Induces CENP-A Chromatin Depletion

Raquel Oliveira & Inês Milagre (with Inês Milagre). 2020. Open Biology
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Paper

Gender Differences in Global but Not Targeted Demethylation in iPSC Reprogramming

Inês Milagre (with Milagre, I.). 2017. Cell Reports
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Paper

Impairment of DNA Methylation Maintenance Is the Main Cause of Global Demethylation in Naive Embryonic Stem Cells

Inês Milagre (with von Meyenn, F.). 2016. Molecular Cell
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Paper

MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs

Inês Milagre (with Eckersley-Maslin, M.A.). 2016. Cell Reports
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Paper

Demethylation of the coding region triggers the activation of the human testis-specific PDHA2 gene in somatic tissues

Inês Milagre (with Pinheiro, A.). 2012. PLoS ONE
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Paper

Marked change in the balance between CYP27A1 and CYP46A1 mediated elimination of cholesterol during differentiation of human neuronal cells

Inês Milagre (with Milagre, I.). 2012. Neurochemistry International
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Paper

Neuronal differentiation alters the ratio of Sp transcription factors recruited to the CYP46A1 promoter

Inês Milagre (with Milagre, I.). 2012. Journal of Neurochemistry
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Paper

Okadaic acid inhibits the trichostatin A-mediated increase of human CYP46A1 neuronal expression in a ERK1/2-Sp3-dependent pathway

Inês Milagre (with Nunes, M.J.). 2012. Journal of Lipid Research
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Paper

Chromatin-modifying agents increase transcription of CYP46A1, a key player in brain cholesterol elimination

Inês Milagre (with Milagre, I.). 2010. Journal of Alzheimer's Disease
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Paper

Sp proteins play a critical role in histone deacetylase inhibitor-mediated derepression of CYP46A1 gene transcription

Inês Milagre (with Nunes, M.J.). 2010. Journal of Neurochemistry
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Paper

Glutathione S-transferase pi regulates UV-induced JNK signaling in SH-SY5Y neuroblastoma cells

Inês Milagre (with Castro-Caldas, M.). 2009. Neuroscience Letters
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Paper

Transcriptional regulation of the human CYP46A1 brain-specific expression by Sp transcription factors

Inês Milagre (with Milagre, I.). 2008. Journal of Neurochemistry
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