Bruno António Caetano Cardoso

Assistant Professor

Generic Bio

Participation in Católica Medical School

  • Coordinator of the curricular unit Growth and Development I 
  • Co-coordinator of curricular unit Growth and Development II 
  • Lectures in curricular units Growth and Development I, Regulation and Integration and Growth and Development II
  • Tutor in curricular units Growth and Development I, Regulation and Integration and Growth and Development II
  • Mentor 
     

Field of Work

Cell and Molecular Biology | Epigenetics | Hemato-Oncology 

 

Professional Activity

  • Católica Medical School (FM-UCP) 
  • Centre for Interdisciplinary Research in Health (CIIS) - CatólicaMed Platform 
     

Education 

  • 2005 - Licentiate Degree in Microbial Biology and Genetics (Faculty of Sciences of the University of Lisbon) 
  • 2011 - PhD in Biomedical Sciences (Faculty of Medicine of the University of Lisbon)  


Summary of Professional Career

  • 2004 - 2005 - Internship at the Institute of Molecular Medicine (IMM) - research group of Prof. João Barata 
  • 2006 - 2011 - PhD student at the Instituto de Medicina Molecular (IMM) - research group of Prof. João Barata 
  • 2012 - Postdoctoral fellow at the Instituto de Medicina Molecular (IMM) - research group of Prof. João Barata 
  • 2012 - 2016 - Postdoctoral fellowship at the Portuguese Institute of Oncology of Lisbon (IPOL-FG)/Centre for Chronic Disease Studies (CEDOC) - research group of Prof. António Almeida 
  • 2016 - 2018 - Postdoctoral researcher at the Institute of Molecular Medicine - João Lobo Antunes (IMM-JLA) - research group of Prof. João Barata 
  • 2018 - 2021 - Senior Researcher at the Institute of Molecular Medicine - João Lobo Antunes (IMM-JLA) - research group of Prof. João Barata  


Languages

Portuguese | English

 

Other Interests

  • Sports
  • Politics
  • History
  • Cinema  
Paper

CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia

Bruno António Caetano Cardoso (with Bruno A. Cardoso). 2023. Haematologica
Paper

Center for Interdisciplinary Research in Health (CIIS) National Meeting 2023

Bruno António Caetano Cardoso 2023. BMC Proceedings
Paper

The Bone Marrow Niche - The Tumor Microenvironment That Ensures Leukemia Progression.

Bruno António Caetano Cardoso 2020. Advances in experimental medicine and biology
Paper

Acetylation drives hepatocyte nuclear factor 1β stability by blocking proteasome-mediated degradation

Bruno António Caetano Cardoso (with Lopes-Coelho, F.). 2019. Journal of Cellular Biochemistry
Paper

Vorinostat synergizes with antioxidant therapy to target myeloproliferative neoplasms

António Almeida & Bruno António Caetano Cardoso (with Cardoso, B.A.). 2019. Experimental Hematology
Paper

STAT5 is essential for IL-7–mediated viability, growth, and proliferation of T-cell acute lymphoblastic leukemia cells

Bruno António Caetano Cardoso (with Daniel Ribeiro). 2018. Blood Advances
Paper

From the outside, from within: Biological and therapeutic relevance of signal transduction in T-cell acute lymphoblastic leukemia

Bruno António Caetano Cardoso (with Oliveira, M.L.). 2017. Cellular Signalling
Paper

RAC1b overexpression stimulates proliferation and NF-κB-mediated antiapoptotic signaling in thyroid cancer cells

Bruno António Caetano Cardoso (with Faria, M.). 2017. PLoS ONE
Paper

FOXP3 can modulate TAL1 transcriptional activity through interaction with LMO2

Bruno António Caetano Cardoso (with Fleskens, V.). 2016. Oncogene
Paper

Optimal interleukin-7 receptor-mediated signaling, cell cycle progression and viability of t-cell acute lymphoblastic leukemia cells rely on casein kinase 2 activity

Bruno António Caetano Cardoso (with Melão, A.). 2016. Haematologica
Paper

Epigenetic Alterations in Fanconi anaemia: Role in pathophysiology and therapeutic potential

António Almeida & Bruno António Caetano Cardoso (with Belo, H.). 2015. PLoS ONE
Paper

PI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemia

Bruno António Caetano Cardoso (with Silveira, A.B.). 2015. Oncotarget
Paper

The bone marrow-mediated protection of myeloproliferative neoplastic cells to vorinostat and ruxolitinib relies on the activation of JNK and PI3K Signalling Pathways

António Almeida & Bruno António Caetano Cardoso (with Cardoso, B.A.). 2015. PLoS ONE
Paper

Activity of the clinical-stage CK2-specific inhibitor CX-4945 against chronic lymphocytic leukemia

Bruno António Caetano Cardoso (with Martins, L.R.). 2014. Leukemia
Paper

Vorinostat Induces Apoptosis and Differentiation in Myeloid Malignancies: Genetic and Molecular Mechanisms

António Almeida & Bruno António Caetano Cardoso (with Silva, G.). 2013. PLoS ONE
Other

IL-4 and TAL1 in T-cell acute lymphoblastic leukemia : studies on the participation of microenvironmental cues and cell-autonomous alterations in leukemogenesis

Bruno António Caetano Cardoso (with Cardoso, Bruno António Caetano, 1982-). 2011.
Paper

IL-7 contributes to the progression of human T-cell acute lymphoblastic leukemias

Bruno António Caetano Cardoso (with Silva, A.). 2011. Cancer Research
Paper

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

Bruno António Caetano Cardoso (with Zenatti, P.P.). 2011. Nature Genetics
Paper

TAL1/SCL is downregulated upon histone deacetylase inhibition in T-cell acute lymphoblastic leukemia cells

Bruno António Caetano Cardoso (with Cardoso, B.A.). 2011. Leukemia
Paper

Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human γδ T-cells

Bruno António Caetano Cardoso (with Correia, D.V.). 2009. PLoS ONE
Paper

Interleukin-4 stimulates proliferation and growth of T-cell acute lymphoblastic leukemia cells by activating mTOR signaling

Bruno António Caetano Cardoso (with Cardoso, B.A.). 2009. Leukemia
Paper

Aberrant signaling in T-cell acute lymphoblastic leukemia: Biological and therapeutic implications

Bruno António Caetano Cardoso (with Cardoso, B.A.). 2008. Brazilian Journal of Medical and Biological Research
Paper

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

Bruno António Caetano Cardoso (with Silva, A.). 2008. Journal of Clinical Investigation